Posts Tagged ‘drug’

American Heart Association Comment: Advisory Committee Recommends that U.S. Food and Drug Administration Keep …
DALLAS, July 14 /PRNewswire-USNewswire/ — After two days of hearings, an advisory committee to the U.S. Food and Drug Administration (FDA) recommended that the FDA allow the type 2 diabetes drug rosiglitazone (brand name, Avandia), to stay on the market, but with most committee members suggesting that the label be revised to include increased warnings. Rosiglitazone is one in a class of drugs …

Experts urge US to restrict drug Avandia
A majority of members of a key advisory committee have recommended that the US government allow diabetes drug Avandia to stay on the market with greater restrictions on its sale.

Avandia Heart Risks Buried by Drug Company: Report
Report shows diabetes drug maker knew 11 years ago that Avandia caused heart problems.

Feds rethink drug recall process
The arthritis pill Vioxx was withdrawn but menopause hormones were not, even though both were tied to heart risks. A multiple sclerosis medicine was pulled and later allowed back on.

When is a drug too risky to stay on the market?
By MARILYNN MARCHIONE AP Medical Writer The arthritis pill Vioxx was withdrawn but menopause hormones were not, even though both were tied to heart risks. A multiple sclerosis medicine was pulled and later…

New Type 2 Drug Could Improve Blood Glucose Control For Some People With Diabetes
A new oral drug for Type 2 diabetes, dapagliflozin, has been identified as potentially helpful for people who have problems controlling blood glucose levels just using metformin. In a study of 534 people by researchers at Aston University in Birmingham, when the drug was used in combination with metformin it was found to improve blood glucose control and lower bodyweight, acting independently of …

Study finds serious heart risks with diabetes drug
A LARGE US study has reported serious heart risks with a drug used to treat type 2 diabetes.

Studies find Glaxo drug has heart risks
WASHINGTON — Two teams of researchers have produced powerful new evidence that the diabetes drug Avandia increases the risk of heart problems and strokes, renewing questions about the safety of the medication.

FDA recently approved a new injectable drug to help control blood sugar in adult patients with Type 1 and Type 2 diabetes. It’s called Symlin, or pramlintide acetate, and it’s manufactured by Amylin Pharmaceuticals. Symlin is used in addition to insulin to help reduce postprandial blood sugar levels in patients who can’t achieve adequate control despite optimal insulin therapy. Tighter control of blood sugar may help reduce the risk of long-term renal, cardiovascular and ocular events in these patients. Although patients with Type 2 diabetes already have drug therapy other than insulin to help control blood sugar, Symlin will be the only therapy available other than insulin for Type 1 patients. The FDA and the manufacturer have some safety concerns about Symlin. First, the drug may increase the risk of hypoglycemia. This risk is greatest in Type 1 diabetics and in those with gastroparesis. Second, patients might mix Symlin with insulin in the same syringe, which can alter the activity of the insulin. And third, the drug might be used inappropriately in patient populations where the risk / benefit profile hasn’t been established. To help resolve these concerns, FDA is requiring that patients receive a Medication Guide with each prescription that explains the risks and how to use the drug properly. The guide tells patients they must be using their insulin as prescribed, must follow their doctor’s instructions on using the drug, must be followed up frequently, and that they …

Study links diabetes drug to strokes
A new US study led by a federal drug safety expert ties the controversial diabetes drug Avandia to a higher risk of heart problems and strokes in older adults.